Each day, more than 1,600 people prematurely die from cancer in the United States. Worldwide, an estimated 20,000 succumb to cancer on a daily basis. For a time, the war on cancer initially waged by Richard Nixon in the ’60s, and the promise of targeted cancer drugs gave hope.
Alas, they’ve all failed to live up to expectations, and have done nothing to improve cancer death rates. Globally, $91 billion was spent on cancer treatments in 2013. In 2014, no cancer drug was approved costing less than $100,000 for a course of treatment.
Yet, despite their exorbitant price tags, they offer little in terms of survival. Tarceva, for example, increases the median survival for pancreatic cancer patients by a mere 10 days. Meanwhile, there are inexpensive, non-patentable therapies available that could be truly game-changing.
One such therapy is high-dose vitamin C. Another is nutritional ketosis — and oncologists in Turkey have presented evidence showing the combination of these two strategies have the ability to “turbo-charge” conventional chemo protocols, making them incredibly effective, and far safer to boot.
Vitamin C Improves Effectiveness of Chemo and Radiation
Research has shown vitamin C is selectively cytotoxic to cancer cells when administered intravenously (IV) or in a liposomal form in high doses. The mechanism behind vitamin C’s ability to selectively target cancer cells has to do with the generation of hydrogen peroxide, which is ultimately what kills the cancer cells.
Normal tissues remain unharmed by the high levels of hydrogen peroxide generated because healthy cells have several ways to remove it, thereby preventing buildup to toxic levels.
One of the primary pathways of removal is the enzyme catalase, and cells with reduced catalase activity — such as cancer cells — are more prone to die from excess reactive oxygen species and secondary free radicals when exposed to high amounts of vitamin C.
Recent research6 also shows high-dose vitamin C administration in combination with chemotherapy and radiation significantly improves the effectiveness of these treatments.
Cancer cells have unstable iron particles (also known as redox-active iron molecules), which makes them more vulnerable to oxidative damage caused by high-dose vitamin C.
When redox-active iron reacts with vitamin C, hydrogen peroxide and associated free radicals are generated, which damage the cancer cells’ DNA and weaken them, thereby making them more vulnerable to the effects of chemo and radiation. As noted by one of the study’s co-authors, Garry Buettner, Ph.D.:
“This paper reveals metabolic frailty in cancer cells that is based on their own production of oxidizing agents that allows us to utilize existing redox-active compounds, like vitamin C, to sensitize cancer cells to radiation [therapy] and chemotherapy.”
Vitamin C Doubles Survival Rate of Brain Cancer Patients Treated With Radiation
To evaluate the safety of vitamin C, 11 patients with glioblastoma (a highly malignant and aggressive type of brain cancer) received high-dose vitamin C IV treatments three times a week for two months while undergoing radiation therapy, followed by two weekly infusions for another seven months. As reported by Time Magazine:
“So far, half of the people in the study were alive nearly two years later. The average survival for the disease is generally around a year.
In a separate study designed to get an early sense of the vitamin’s effectiveness, the researchers also tested high-dose vitamin C in a group of 14 people with non-small cell lung cancer.
So far, 93 percent of the people receiving the vitamin C infusions are responding to chemotherapy and radiation, compared to 40 percent who usually do.
In an encouraging finding, more than 30 percent of the people getting the vitamin C also showed signs of their tumors shrinking. Usually, only 15 percent to 19 percent of people receiving chemo and radiation see their tumors get smaller.”
In the second phase of the trial, the researchers will investigate vitamin C’s effects on patients with stage 4 lung cancer and other aggressive cancers.
Vitamin C and Nutritional Ketosis Is a Winning Combination
While the featured research is certainly on the right track, an oncology center in Turkey has taken it a step further, showing that vitamin C in combination with nutritional ketosis improves the effectiveness of chemotherapy to such a degree that a minimal dose can be used to treat even the most aggressive and advanced cancers.
I recently interviewed Dr. Abdul Kadir Slocum from the ChemoThermia Oncology Center in Turkey about this research. If you missed it, you’d be well advised to watch it now, because this metabolically supported therapy is truly groundbreaking, offering hope where previously there was none.
In summary, metabolically supported chemotherapy involves applying chemotherapy with a variety of interventions to support its effectiveness. This includes the use of high-dose vitamin C, a ketogenic diet, hyperthermia, glycolytic inhibitors, and hyperbaric oxygen therapy, just to name a few.
All oncology patients at the center are put on a ketogenic diet, which creates metabolic stress on the cancer cells.
Then, prior to administering the chemo, the patient will do a minimum 14-hour fast (Slocum recommends fasting as long as possible, but a minimum of 14 hours is required), which further increases the metabolic stress on the cancer cells.